Intracellular superoxide level controlled by manganese superoxide dismutases affects trichothecene production in Fusarium graminearum
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چکیده
منابع مشابه
Superoxide Dismutases and Superoxide Reductases
Yuewei Sheng,† Isabel A. Abreu,*,‡,§ Diane E. Cabelli,* Michael J. Maroney,* Anne-Frances Miller,* Miguel Teixeira,*,‡ and Joan Selverstone Valentine*,†,∇ †Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California 90095, United States ‡Instituto de Tecnologia Química e Bioloǵica Antońio Xavier, Universidade Nova de Lisboa, Av. da Repub́lica, 2780-157...
متن کاملSuperoxide radical and superoxide dismutases.
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH. production from H2O2. There is a glycosylate...
متن کاملManganese and iron superoxide dismutases are structural homologs.
The crystal structure of a tetrameric manganese superoxide dismutase from a thermophilic bacterium, Thermus thermophilus HB8, has been determined at 4.4-A resolution by local averaging of electron density maps calculated by isomorphous replacement. The spatial arrangement of the principal secondary structural features of iron superoxide dismutase is conserved in manganese dismutase. The structu...
متن کاملPrecocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum
Precocene II, a constituent of essential oils, shows antijuvenile hormone activity in insects and inhibits trichothecene production in fungi. We investigated the molecular mechanism by which precocene II inhibits trichothecene production in Fusarium graminearum, the main causal agent of Fusarium head blight and trichothecene contamination in grains. Voltage-dependent anion channel (VDAC), a mit...
متن کاملSuperoxide dismutases in parasitoids' venom
Background: Endoparasitoid wasps inject venom proteins at oviposition to alter host immunity. Results: The venom of Leptopilina boulardi but not of a related species contains an active extracellular SOD. Recombinant SODs inhibit the Drosophila host phenoloxidase activity. Conclusion: An extracellular SOD is secreted and active in an insect fluid. Significance: SODs may be used as immune suppres...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2017
ISSN: 1574-6968
DOI: 10.1093/femsle/fnx213